Dominator Prototypes
| Tier | Prototype | Name | Rarity | Synergy |
| SS |  | Pain Rune | Epic | Prism Amulet, Flashpoint |
| SS |  | Vision Stone | Epic | Dominate/ Ultima Ring, Treant Heart |
| SS |  | Dominant Nucleus | Mythic | - |
| S+ |  | Fifth Element | Mythic | Prism Amulet, Flashpoint |
| S+ |  | Thorn of Glory | Mythic | Prism Amulet, Flashpoint |
| S+ |  | Dark Summit | Epic | - |
| S |  | Solar Flare | Mythic | - |
| S |  | Ring of Greed | Mythic | - |
| S |  | Phantom Cloak | Mythic | - |
| S |  | Flowing Rune | Epic | - |
| S |  | Preying Eyes | Epic | - |
| S |  | Soaring Medaillon | Elite | |
| S |  | Chaos Chip | Elite | Flashpoint, Ancestral Will |
| A |  | Attract Beholder | Mythic | |
| A |  | Apocalypse Cloak | Mythic | |
| A |  | Redthorn Rune | Epic | |
| B |  | Orb of Domination | Epic | Dominate, Scholar's Monument |
| B |  | Power Word: Pain | Elite | |
| F |  | Bloodlust | Elite | |
| F |  | Iron Oath | Rare | |
| F |  | Bladefury | Rare | |
| F |  | Inner Fire | Rare |
Tenicity Prototypes
| Tier | Prototype | Name | Rarity | Synergy |
| SS |  | Prism Amulet | Mythic | Preying Eyes/ Orb of Domination |
| S+ |  | Ruler's Ring | Mythic | Dominant Nucleus |
| S+ |  | Company of Heroes | Epic | |
| S+ |  | Astral Strike | Epic | |
| S+ |  | Ancestral Will | Elite | |
| S |  | Dominate | Epic | Vision Stone, Treant Heart |
| S |  | Ultima Ring | Elite | Vision Stone, Treant Heart |
| A |  | Helios | Rare | |
| B |  | Blood Thirsty Crest | Mythic | Fifth Element, Pain Rune, Preying Eyes |
| F |  | Gold Asterism | Rare | |
| F |  | Earth Power | Rare |
Enlightenment Prototypes
| Tier | Prototype | Name | Rarity | Synergy |
| SS |  | Horn of Healing | Mythic | |
| SS |  | Flashpoint | Epic | Pain Rune |
| S |  | Coronate | Elite | |
| A |  | Treant Heart | Epic | |
| B |  | Scholar's Monument | Epic | |
| B |  | Temporal Beetle | Epic | Vision Stone, Astral Strike/ Dominate |
| F |  | Luna Box | Elite | |
| F |  | Zoisite Shard | Rare | |
| F |  | Brilliance | Rare |